L-Theanine
L-Theanine
Base Peptides are intended for licensed medical professionals and experienced researchers. Reconstitution required. Dosing and use instructions are not provided.
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$15.00
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$15.00
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L-Theanine — γ-Glutamyl-ethylamide (Amino Acid from Green Tea)
L-Theanine is a naturally occurring amino acid best known from green tea leaves. In research models it’s used to explore calm focus, stress modulation, and sleep-adjacent relaxation without sedation, through gentle effects on glutamate/GABA signaling and brain-wave patterns.
Identifiers
- Synonyms: N-Ethyl-L-glutamine; γ-glutamyl-ethylamide; L-Theanine
- CAS No.: 3081-61-6
- Formula / MW: C7H14N2O3 • ~174.20 g·mol⁻¹
- Class: Non-proteinogenic amino acid (tea amino acid)
How It Works (Plain English)
- Structurally similar to glutamate; can influence glutamatergic signaling and support GABAergic tone in models.
- Frequently associated with increases in alpha brain-wave activity (relaxed alertness) and improved attention when paired with stimuli.
- Also studied for gentle effects on stress physiology (perceived stress, heart-rate variability) and sleep quality endpoints.
Why Researchers Use It
- To investigate mechanisms of calm focus and attentional control without stimulant confounds.
- To assess stress-response and sleep-adjacent outcomes with a favorable tolerability profile in models.
- As a synergy probe with caffeine in cognition/attention paradigms.
Key Study Themes — What’s Typically Observed
Calm Focus / EEG Alpha
- Endpoints: EEG alpha power, sustained-attention tasks, perceived calmness.
- Typical findings: Increases in alpha activity and subjective calm; task performance benefits depend on design and dose.
- Why it matters: Useful tool for studying non-sedating relaxation and attentional engagement.
Stress & Sleep-Adjacent Outcomes
- Endpoints: HRV, cortisol (design-dependent), sleep latency/quality questionnaires.
- Typical findings: Modest improvements in perceived stress and sleep metrics in select cohorts.
- Design notes: Control for caffeine intake and testing time; effects can be subtle and context-specific.
Potential Research Applications
Cognition & Attention
- Continuous-performance tests, reaction time, error rates
Stress Modulation
- Perceived stress scales, HRV, startle/adaptability tasks
Sleep & Recovery
- Sleep quality indices, latency, next-day alertness
Synergistic / Comparator Compounds
Caffeine (Synergy)
- Why pair: Classic combo for alertness with smoother subjective feel vs caffeine alone.
Magnesium Glycinate
- Why pair: Relaxation/sleep-adjacent research without strong sedation.
L-Tyrosine (Comparator)
- Why compare: Attention under stress (catecholamine support) vs theanine’s calming focus.
Known Concerns (Context)
- Mildness & variability: Effects are generally subtle and design-dependent.
- Interactions: Usually well-tolerated; still consider interactions with psychoactive agents in research designs.
- General: For laboratory research use only; not for human consumption or therapeutic use.
Specifications & Handling
- Form: Research-grade powder or capsules (lot-coded)
- Purity: ≥ 98–99% (HPLC/MS verified)
- Storage: Cool, dry; protect from light/moisture
- In solution: Water-soluble; document pH, concentration, and time-to-assay
- Labeling: Tamper-evident; research-use-only; lot/SKU displayed
Regulatory & Use Notice
Sold for laboratory research use only. Not for human consumption, medical, or veterinary use. No human-use instructions are provided. Buyer is responsible for safe handling and regulatory compliance.
L-Theanine Research | Calm Focus, Stress Modulation & Sleep-Adjacent Outcomes | Tea Amino Acid
