L-Glutamine
L-Glutamine
Base Peptides are intended for licensed medical professionals and experienced researchers. Reconstitution required. Dosing and use instructions are not provided.
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$20.00
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$20.00
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L-Glutamine — Conditioned-Essential Amino Acid (Cellular Fuel & Gut Integrity)
L-Glutamine is the most abundant amino acid in the human body. In research settings it supports cellular energy metabolism, gut barrier function, immune response, and muscle recovery. Its diverse role makes it a core molecule for studies of metabolism, stress adaptation, and tissue repair.
Identifiers
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Synonyms: L-Glutamic acid amide; (S)-2-Amino-4-carbamoylbutanoic acid
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CAS No.: 56-85-9
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Formula / MW: C5H10N2O3 • ~146.15 g·mol⁻¹
- Class: Non-essential (conditionally essential) amino acid
How It Works (Plain English)
- Acts as a primary nitrogen donor for building proteins, nucleotides, and antioxidants like glutathione.
- Serves as the main fuel source for rapidly dividing cells such as enterocytes (gut) and lymphocytes (immune system).
- Supports gut-barrier integrity and intestinal permeability balance in stress or injury models.
Why Researchers Use It
- To study cellular metabolism, immune activation, and gut-epithelial recovery.
- To examine skeletal-muscle protein turnover and recovery following exercise or trauma.
- To assess stress-response pathways involving heat shock proteins, cortisol, and cytokines.
Key Study Themes — What’s Typically Observed
Muscle Recovery & Protein Turnover
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Endpoints: Plasma glutamine, muscle glycogen, nitrogen balance, protein synthesis markers.
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Findings: Glutamine depletion linked to catabolism; supplementation normalizes nitrogen balance and supports recovery models.
- Why it matters: Central to research on anabolic-catabolic balance after exercise or injury.
Gut Integrity & Immune Function
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Endpoints: Tight-junction proteins, permeability assays, cytokine profiles.
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Findings: Enhanced mucosal repair and lower inflammatory markers in stress and infection models.
- Why it matters: Key molecule for intestinal health, immune readiness, and systemic resilience.
Potential Research Applications
Metabolic & Cellular Energy
- ATP generation, Krebs-cycle flux, nitrogen shuttling.
Gut Barrier & Microbiome
- Enterocyte fuel, permeability, microbial balance.
Muscle Recovery & Performance
- Protein synthesis, fatigue markers, recovery kinetics.
Synergistic / Comparator Compounds
L-Theanine / N-Acetyl L-Tyrosine
- Why pair: Combine cognitive-calming and stress-modulation effects with cellular recovery amino acids.
BPC-157 / TB-500 (Peptides)
- Why pair: Peptide-driven tissue repair complemented by amino-acid support of cell growth and metabolism.
Creatine / Beta-Alanine
- Why compare: Evaluate energy-buffering vs nitrogen-shuttling roles in exercise-based studies.
Known Concerns
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Ammonia balance: Excess glutamine can increase ammonia formation in hepatic-impaired models.
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Conditional essentiality: Typically non-essential but required during trauma, infection, or heavy stress.
- General: For laboratory research use only; not for human consumption or therapeutic use.
Specifications & Handling
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Form: Crystalline powder or capsules (lot-coded)
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Purity: ≥ 99 % (HPLC/MS verified)
- Storage: Cool, dry, sealed; protect from light and moisture
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In solution: Stable in aqueous buffers; avoid prolonged storage > 24 h once dissolved.
- Labeling: Tamper-evident; “Research use only”; lot/SKU displayed.
Regulatory & Use Notice
Sold for laboratory research use only. Not for human consumption, medical, or veterinary use. No human-use instructions are provided. Buyer is responsible for safe handling and regulatory compliance.
L-Glutamine Research Compound | Cellular Fuel, Gut Integrity & Muscle Recovery Studies
