Alpha GPC Capsules
Alpha GPC Capsules
Base Peptides are intended for licensed medical professionals and experienced researchers. Reconstitution required. Dosing and use instructions are not provided.
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Alpha-GPC — L-Alpha-Glycerylphosphorylcholine (Choline Donor Compound)
Alpha-GPC is a natural choline-containing phospholipid precursor studied for its ability to support acetylcholine synthesis, cognitive performance, and neuro-cellular membrane integrity. It delivers bioavailable choline across the blood-brain barrier and plays a key role in research on focus, learning, and neuroprotection.
- Synonyms: L-Alpha-Glycerylphosphorylcholine, Alpha-GPC, Choline Alfoscerate
- CAS No.: 28319-77-9
- Formula / MW: C8H20NO6P • ~257.22 g·mol⁻¹
- Class: Natural phospholipid metabolite / choline donor
- Supplies free choline for synthesis of the neurotransmitter acetylcholine, central to memory and attention.
- Supports phosphatidylcholine and cell-membrane integrity within neuronal tissue.
- Crosses the blood-brain barrier efficiently, distinguishing it from many other dietary choline sources.
- To investigate neurotransmitter synthesis and cognitive performance markers.
- To explore neuroprotective and membrane-repair mechanisms following hypoxia or injury models.
- To assess choline bioavailability vs phosphatidylcholine, CDP-choline, and other donors.
Key Study Themes — What’s Typically Observed
Cognition & Memory Models
- Endpoints: Memory recall, focus tests, acetylcholine levels, brain imaging (PET or fMRI).
- Findings: Enhanced cholinergic activity, improved reaction time and short-term recall in aged or stressed models.
- Why it matters: Demonstrates Alpha-GPC’s role as a rapid and efficient choline source.
Neuroprotection & Cell Integrity
- Endpoints: Neuronal survival, phosphatidylcholine synthesis, oxidative markers.
- Findings: Protective effects on neuronal membranes under oxidative or ischemic stress in vitro and in vivo.
- Why it matters: Provides a model for studying membrane repair and neurotransmission recovery after injury.
Potential Research Applications
Cognitive Performance & Learning
- Attention, working memory, and reaction-time studies.
Neuroprotection & Aging
- Models of hypoxia, oxidative stress, and neurodegeneration.
Choline Metabolism Research
- Comparative choline kinetics vs CDP-choline and phosphatidylcholine.
Synergistic / Comparator Compounds
Uridine Monophosphate (UMP)
- Why pair: Combined choline + uridine + DHA research (“Kennedy Pathway”) for synaptic-membrane synthesis.
L-Theanine / Caffeine
- Why pair: Explore attentional focus from Alpha-GPC’s cholinergic tone with alertness modulation.
Citicoline (CDP-Choline)
- Why compare: Both provide bioavailable choline; differing metabolic routes and phospholipid impact.
Known Concerns (Context)
- Transient cholinergic effects: Headache or mild gastrointestinal upset observed at high doses in some human data.
- Population notes: Individuals with cholinergic hypersensitivity may exhibit variability in response.
- General: For laboratory research use only; not for human consumption or therapeutic use.
Specifications & Handling
- Form: Hygroscopic powder or encapsulated solid (lot-coded)
- Purity: ≥ 98 % (HPLC/MS verified)
- Storage: Store ≤ 25 °C, dry, sealed; protect from humidity and light
- Handling notes: Hygroscopic — reseal promptly; avoid long-term exposure to air.
- Labeling: Tamper-evident; lot/SKU and expiry clearly displayed.
Regulatory & Use Notice
Sold for laboratory research use only. Not for human consumption, medical, or veterinary use. No human-use instructions are provided. Buyer is responsible for safe handling and regulatory compliance.
Alpha-GPC Research Compound | Choline Donor | Cognitive Performance & Neuroprotection Studies
